Hiya,
It's definitely possible to use Arduino products with Alexa, but depending on what you want to do it could be very possible or possible with some extra work with hardware or software depending on what you want to do. Do you have some boards already? What are you looking to do/make? More details help!
For example, there are tons of projects to look through that might be close to what you want:
https://create.arduino.cc/projecthub/projects/tags/alexaMany Alexa/Arduino projects use the Arduino IoT Cloud for most of the work, and unfortunately, that requires some specific Arduino boards for compatibility if you were looking to use that method.
Let me know!
Best,
RĂ©na