I am hoping there is a factory reset or method to halt an upload when the board is powered (so I can clear / replace what I uploaded).

What I uploaded has some code in the loop which causes the board to get stuck (ie: an infinite loop). Thus the TinyScreen+ does not show up as a USB recognizable device, and I can not upload anything to it.

Anyone know how to clear this situation?

Thanks

With USB connector oriented at the top - put the power switch to off (down). Then, while pressing the button closest to the USB connector (top button on power switch side), flip the power switch to on (up). This puts the TinyScreen+ into bootloader mode only, ready for sketch upload. I just had the same issue, thought for a while I had completely bricked the TinyScreen+, but this saved me!